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RNA Signal Amplifier Circuit with Integrated Fluorescence Output
[Image: see text] We designed an in vitro signal amplification circuit that takes a short RNA input that catalytically activates the Spinach RNA aptamer to produce a fluorescent output. The circuit consists of three RNA strands: an internally blocked Spinach aptamer, a fuel strand, and an input stra...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487219/ https://www.ncbi.nlm.nih.gov/pubmed/25354355 http://dx.doi.org/10.1021/sb500314r |