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Engineering Escherichia coli into a Protein Delivery System for Mammalian Cells

[Image: see text] Many Gram-negative pathogens encode type 3 secretion systems, sophisticated nanomachines that deliver proteins directly into the cytoplasm of mammalian cells. These systems present attractive opportunities for therapeutic protein delivery applications; however, their utility has be...

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Detalles Bibliográficos
Autores principales: Reeves, Analise Z., Spears, William E., Du, Juan, Tan, Kah Yong, Wagers, Amy J., Lesser, Cammie F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487226/
https://www.ncbi.nlm.nih.gov/pubmed/25853840
http://dx.doi.org/10.1021/acssynbio.5b00002