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Structure and mechanism of a bacterial host-protein citrullinating virulence factor, Porphyromonas gingivalis peptidylarginine deiminase

Citrullination is a post-translational modification of higher organisms that deiminates arginines in proteins and peptides. It occurs in physiological processes but also pathologies such as multiple sclerosis, fibrosis, Alzheimer’s disease and rheumatoid arthritis (RA). The reaction is catalyzed by...

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Detalles Bibliográficos
Autores principales: Goulas, Theodoros, Mizgalska, Danuta, Garcia-Ferrer, Irene, Kantyka, Tomasz, Guevara, Tibisay, Szmigielski, Borys, Sroka, Aneta, Millán, Claudia, Usón, Isabel, Veillard, Florian, Potempa, Barbara, Mydel, Piotr, Solà, Maria, Potempa, Jan, Gomis-Rüth, F. Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487231/
https://www.ncbi.nlm.nih.gov/pubmed/26132828
http://dx.doi.org/10.1038/srep11969