A Critical Role of the mTOR/eIF2α Pathway in Hypoxia-Induced Pulmonary Hypertension

Enhanced proliferation of pulmonary arterial vascular smooth muscle cells (PASMCs) is a key pathological component of vascular remodeling in hypoxia-induced pulmonary hypertension (HPH). Mammalian targeting of rapamycin (mTOR) signaling has been shown to play a role in protein translation and partic...

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Detalles Bibliográficos
Autores principales: Wang, Ai-ping, Li, Xiao-hui, Yang, Yong-mei, Li, Wen-qun, Zhang, Wang, Hu, Chang-ping, Zhang, Zheng, Li, Yuan-jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487252/
https://www.ncbi.nlm.nih.gov/pubmed/26120832
http://dx.doi.org/10.1371/journal.pone.0130806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487252/
https://www.ncbi.nlm.nih.gov/pubmed/26120832
http://dx.doi.org/10.1371/journal.pone.0130806

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