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Sulforaphane Reverses the Expression of Various Tumor Suppressor Genes by Targeting DNMT3B and HDAC1 in Human Cervical Cancer Cells

Sulforaphane (SFN) may hinder carcinogenesis by altering epigenetic events in the cells; however, its molecular mechanisms are unclear. The present study investigates the role of SFN in modifying epigenetic events in human cervical cancer cells, HeLa. HeLa cells were treated with SFN (2.5 µM) for a...

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Detalles Bibliográficos
Autores principales: Ali Khan, Munawwar, Kedhari Sundaram, Madhumitha, Hamza, Amina, Quraishi, Uzma, Gunasekera, Dian, Ramesh, Laveena, Goala, Payal, Al Alami, Usama, Ansari, Mohammad Zeeshan, Rizvi, Tahir A., Sharma, Chhavi, Hussain, Arif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487331/
https://www.ncbi.nlm.nih.gov/pubmed/26161119
http://dx.doi.org/10.1155/2015/412149