Cargando…

Specific synaptopathies diversify brain responses and hearing disorders: you lose the gain from early life

Before hearing onset, inner hair cell (IHC) maturation proceeds under the influence of spontaneous Ca(2+) action potentials (APs). The temporal signature of the IHC Ca(2+) AP is modified through an efferent cholinergic feedback from the medial olivocochlear bundle (MOC) and drives the IHC pre- and p...

Descripción completa

Detalles Bibliográficos
Autores principales: Knipper, Marlies, Panford-Walsh, Rama, Singer, Wibke, Rüttiger, Lukas, Zimmermann, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487345/
https://www.ncbi.nlm.nih.gov/pubmed/25843689
http://dx.doi.org/10.1007/s00441-015-2168-x