Cargando…

Platelet dysfunction in hypercholesterolemia mice, two Alzheimer’s disease mouse models and in human patients with Alzheimer’s disease

Alzheimer’s disease (AD) is a severe neurodegenerative disorder characterized mainly by accumulation of amyloid-β plaques and neurofibrillary tangles, synaptic and neuronal loss. Blood platelets contain the neurotransmitter serotonin and amyloid-precursor protein (APP), and may thus be useful as a p...

Descripción completa

Detalles Bibliográficos
Autores principales: Plagg, Barbara, Marksteiner, Josef, Kniewallner, Kathrin M., Humpel, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487346/
https://www.ncbi.nlm.nih.gov/pubmed/25947203
http://dx.doi.org/10.1007/s10522-015-9580-1