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Signal loss due to oligomerization in ELISA analysis of amyloid-beta can be recovered by a novel sample pre-treatment method

According to the predominant theories, soluble amyloid-beta (Aβ) aggregates are the principal neurotoxic agents in Alzheimer’s disease pathology, making them a popular target for the development of therapeutics and diagnostic markers. One of the most commonly used methods for determining the concent...

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Detalles Bibliográficos
Autores principales: Janssen, Leen, Sobott, Frank, De Deyn, Peter P., Van Dam, Debby
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487349/
https://www.ncbi.nlm.nih.gov/pubmed/26150979
http://dx.doi.org/10.1016/j.mex.2015.02.011