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Signal loss due to oligomerization in ELISA analysis of amyloid-beta can be recovered by a novel sample pre-treatment method
According to the predominant theories, soluble amyloid-beta (Aβ) aggregates are the principal neurotoxic agents in Alzheimer’s disease pathology, making them a popular target for the development of therapeutics and diagnostic markers. One of the most commonly used methods for determining the concent...
Autores principales: | Janssen, Leen, Sobott, Frank, De Deyn, Peter P., Van Dam, Debby |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487349/ https://www.ncbi.nlm.nih.gov/pubmed/26150979 http://dx.doi.org/10.1016/j.mex.2015.02.011 |
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