Single-nucleotide resolution mapping of m6A and m6Am throughout the transcriptome

N(6)-methyladenosine (m6A) is the most abundant modified base in eukaryotic mRNA and has been linked to diverse effects on mRNA fate. Current m6A mapping approaches localize m6A residues to 100–200 nt-long regions of transcripts. The precise position of m6A in mRNAs cannot be identified on a transcr...

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Detalles Bibliográficos
Autores principales: Linder, Bastian, Grozhik, Anya V., Olarerin-George, Anthony O., Meydan, Cem, Mason, Christopher E., Jaffrey, Samie R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487409/
https://www.ncbi.nlm.nih.gov/pubmed/26121403
http://dx.doi.org/10.1038/nmeth.3453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487409/
https://www.ncbi.nlm.nih.gov/pubmed/26121403
http://dx.doi.org/10.1038/nmeth.3453

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