Cargando…

Transgenic sickle cell disease mice have high mortality and dysregulated immune responses after vaccination

BACKGROUND: Children with sickle cell disease (SCD) are susceptible to recurrent infections, which are often life threatening and necessitate frequent vaccinations. Given the altered baseline immunity and proinflammatory state associated with SCD, we sought to determine the relative safety and effic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Szczepanek, Steven M., Secor, Eric R., Bracken, Sonali J., Guernsey, Linda, Rafti, Ektor, Matson, Adam, Thrall, Roger S., Andemariam, Biree
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487511/ https://www.ncbi.nlm.nih.gov/pubmed/23728384 http://dx.doi.org/10.1038/pr.2013.85

Ejemplares similares

Poor Long-Term Efficacy of Prevnar-13 in Sickle Cell Disease Mice Is Associated with an Inability to Sustain Pneumococcal-Specific Antibody Titers
por: Szczepanek, Steven M., et al.
Publicado: (2016)

Early-Life Antibiotics Attenuate Regulatory T Cell Generation and Increase the Severity of Murine House Dust Mite-Induced Asthma
por: Adami, Alexander J., et al.
Publicado: (2018)

Bromelain Inhibits Allergic Sensitization and Murine Asthma via Modulation of Dendritic Cells
por: Secor, Eric R., et al.
Publicado: (2013)

IgG transmitted from allergic mothers decreases allergic sensitization in breastfed offspring
por: Matson, Adam P, et al.
Publicado: (2010)

Regulation of IgE activity in inhalational tolerance via formation of IgG anti-IgE/IgE immune complexes
por: Bracken, Sonali J., et al.
Publicado: (2018)

P01.22. Identification of a peptide biomarker from bromelain, an extract of ananas comosus merr, using LC-SRM/MS
por: Secor, E, et al.
Publicado: (2012)

Valsartan impedes epinephrine-induced ICAM-4 activation on normal, sickle cell trait and sickle cell disease red blood cells
por: Zhang, Jing, et al.
Publicado: (2019)

Patient Controlled Analgesia for Adults with Sickle Cell Disease Awaiting Admission from the Emergency Department
por: Santos, Josue, et al.
Publicado: (2016)

LC-MS/MS Identification of a Bromelain Peptide Biomarker from Ananas comosus Merr
por: Secor, Eric R., et al.
Publicado: (2012)

Maternal allergy is associated with surface-bound IgE on cord blood basophils
por: Matson, Adam P, et al.
Publicado: (2013)

Annual Academy of Sickle Cell and Thalassaemia (ASCAT) conference: a summary of the proceedings
por: Strunk, Crawford, et al.
Publicado: (2020)

Economic and Clinical Burden of Managing Sickle Cell Disease with Recurrent Vaso-Occlusive Crises in the United States
por: Udeze, Chuka, et al.
Publicado: (2023)

Radioimmunotherapy with tositumomab and iodine-131 tositumomab for non-Hodgkin’s lymphoma
por: Andemariam, Biree, et al.
Publicado: (2007)

Correction to: Economic and Clinical Burden of Managing Sickle Cell Disease with Recurrent Vaso-Occlusive Crises in the United States
por: Udeze, Chuka, et al.
Publicado: (2023)

Oral Bromelain Attenuates Inflammation in an Ovalbumin-induced Murine Model of Asthma
por: Secor, Eric R., et al.
Publicado: (2008)

Regulatory B Cells from Hilar Lymph Nodes of Tolerant Mice in a Murine Model of Allergic Airway Disease are CD5(+), Express TGF-β and Co-localize with CD4(+)Foxp3(+) T Cells
por: Natarajan, Prabitha, et al.
Publicado: (2012)

Serious adverse events in African–American cancer patients with sickle cell trait and inherited haemoglobinopathies in a SEER-Medicare claims cohort
por: Hoag, Jessica R., et al.
Publicado: (2019)

P1432: PATTERNS OF VOXELOTOR USE IN A MULTICENTER, REAL-WORLD STUDY OF PATIENTS WITH SICKLE CELL DISEASE
por: Andemariam, Biree, et al.
Publicado: (2023)

Burden of disease, treatment utilization, and the impact on education and employment in patients with sickle cell disease: A comparative analysis of high‐ and low‐ to middle‐income countries for the international Sickle Cell World Assessment Survey
por: Osunkwo, Ifeyinwa, et al.
Publicado: (2022)

Cbl-b Deficiency in Mice Results in Exacerbation of Acute and Chronic Stages of Allergic Asthma
por: Carson, William F., et al.
Publicado: (2015)

P1439: EPELEUTON, A NOVEL SYNTHETIC Ω-3 FATTY ACID, REDUCES ENDOTHELIAL ADHESION OF RED BLOOD CELLS FROM SICKLE CELL DISEASE PATIENTS UNDER PHYSIOLOGICAL FLOW CONDITIONS
por: Hamza, Moayed, et al.
Publicado: (2023)

Targeting the PXR-TLR4 signaling pathway to reduce intestinal inflammation in an experimental model of necrotizing enterocolitis
por: Huang, Kezhen, et al.
Publicado: (2018)

S268: INTERIM ANALYSIS OF A PHASE 2 TRIAL TO ASSESS THE EFFICACY AND SAFETY OF CRIZANLIZUMAB IN SICKLE CELL DISEASE PATIENTS WITH PRIAPISM (SPARTAN)
por: Anderson, Alan, et al.
Publicado: (2023)

Impact of sickle cell disease on patientsʼ daily lives, symptoms reported, and disease management strategies: Results from the international Sickle Cell World Assessment Survey (SWAY)
por: Osunkwo, Ifeyinwa, et al.
Publicado: (2021)

Evidence that FcRn mediates the transplacental passage of maternal IgE in the form of IgG anti‐IgE/IgE immune complexes
por: Bundhoo, A., et al.
Publicado: (2015)

Mechanism of Testosterone Deficiency in the Transgenic Sickle Cell Mouse
por: Musicki, Biljana, et al.
Publicado: (2015)

Spatiotemporal Alterations in Gait in Humanized Transgenic Sickle Mice
por: Kiven, Stacy, et al.
Publicado: (2020)

Role of microRNA dysregulation in childhood acute leukemias: Diagnostics, monitoring and therapeutics: A comprehensive review
por: Szczepanek, Joanna
Publicado: (2020)

Urinary Bladder Dysfunction in Transgenic Sickle Cell Disease Mice
por: Claudino, Mário Angelo, et al.
Publicado: (2015)

Vaso-Occlusion in Sickle Cell Disease: Is Autonomic Dysregulation of the Microvasculature the Trigger?
por: Veluswamy, Saranya, et al.
Publicado: (2019)

Longitudinal transcriptomic dysregulation in the peripheral blood of transgenic Huntington’s disease monkeys
por: Kocerha, Jannet, et al.
Publicado: (2013)

Improvement of hemolytic anemia with GBT1118 is renoprotective in transgenic sickle mice
por: Ren, Guohui, et al.
Publicado: (2022)

5559749 A MULTICENTER, RETROSPECTIVE STUDY ON REAL-WORLD EXPERIENCE OF PATIENTS WITH SICKLE CELL DISEASE TREATED WITH VOXELOTOR
por: Andemariam, B., et al.
Publicado: (2023)

P1485: A MULTICENTER, RETROSPECTIVE STUDY ON REAL-WORLD EXPERIENCE OF PATIENTS WITH SICKLE CELL DISEASE TREATED WITH VOXELOTOR
por: Andemariam, B., et al.
Publicado: (2022)

Spatiotemporal Dysfunction of the Vascular Permeability Barrier in Transgenic Mice with Sickle Cell Disease
por: Ghosh, Samit, et al.
Publicado: (2012)

Mortality by sickle cell disease in Brazil
por: Arduini, Giovanna Abadia Oliveira, et al.
Publicado: (2017)

microRNA-128a dysregulation in transgenic Huntington’s disease monkeys
por: Kocerha, Jannet, et al.
Publicado: (2014)

Colon dysregulation in methamphetamine self-administering HIV-1 transgenic rats
por: Persons, Amanda L., et al.
Publicado: (2018)

Differential Expression and Function of PDE8 and PDE4 in Effector T cells: Implications for PDE8 as a Drug Target in Inflammation
por: Vang, Amanda G., et al.
Publicado: (2016)

Limitations of mouse models for sickle cell disease conferred by their human globin transgene configurations
por: Woodard, Kaitly J., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_aa9gbdiph7dhliv31h0lmrps5h