Phylogenetically typing bacterial strains from partial SNP genotypes observed from direct sequencing of clinical specimen metagenomic data

We describe an approach for genotyping bacterial strains from low coverage genome datasets, including metagenomic data from complex samples. Sequence reads from unknown samples are aligned to a reference genome where the allele states of known SNPs are determined. The Whole Genome Focused Array SNP...

Descripción completa

Detalles Bibliográficos
Autores principales: Sahl, Jason W., Schupp, James M., Rasko, David A., Colman, Rebecca E., Foster, Jeffrey T., Keim, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487561/
https://www.ncbi.nlm.nih.gov/pubmed/26136847
http://dx.doi.org/10.1186/s13073-015-0176-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487561/
https://www.ncbi.nlm.nih.gov/pubmed/26136847
http://dx.doi.org/10.1186/s13073-015-0176-9

Ejemplares similares