CD103(+)CD11b(+) Dendritic Cells Induce T(h)17 T Cells in Muc2-Deficient Mice with Extensively Spread Colitis

Mucus alterations are a feature of ulcerative colitis (UC) and can drive inflammation by compromising the mucosal barrier to luminal bacteria. The exact pathogenesis of UC remains unclear, but CD4(+) T cells reacting to commensal antigens appear to contribute to pathology. Given the unique capacity...

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Detalles Bibliográficos
Autores principales: Wenzel, Ulf A., Jonstrand, Caroline, Hansson, Gunnar C., Wick, Mary Jo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487685/
https://www.ncbi.nlm.nih.gov/pubmed/26121642
http://dx.doi.org/10.1371/journal.pone.0130750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487685/
https://www.ncbi.nlm.nih.gov/pubmed/26121642
http://dx.doi.org/10.1371/journal.pone.0130750

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