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CD103(+)CD11b(+) Dendritic Cells Induce T(h)17 T Cells in Muc2-Deficient Mice with Extensively Spread Colitis
Mucus alterations are a feature of ulcerative colitis (UC) and can drive inflammation by compromising the mucosal barrier to luminal bacteria. The exact pathogenesis of UC remains unclear, but CD4(+) T cells reacting to commensal antigens appear to contribute to pathology. Given the unique capacity...
Autores principales: | Wenzel, Ulf A., Jonstrand, Caroline, Hansson, Gunnar C., Wick, Mary Jo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487685/ https://www.ncbi.nlm.nih.gov/pubmed/26121642 http://dx.doi.org/10.1371/journal.pone.0130750 |
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