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Nuclear matrix protein Matrin 3 is a regulator of ZAP-mediated retroviral restriction
BACKGROUND: Matrin 3 is a nuclear matrix protein involved in multiple nuclear processes. In HIV-1 infection, Matrin 3 serves as a Rev cofactor important for the cytoplasmic accumulation of HIV-1 transcripts. ZAP is a potent host restriction factor of multiple viruses including retroviruses HIV-1 and...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487854/ https://www.ncbi.nlm.nih.gov/pubmed/26129669 http://dx.doi.org/10.1186/s12977-015-0182-4 |