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Nuclear matrix protein Matrin 3 is a regulator of ZAP-mediated retroviral restriction

BACKGROUND: Matrin 3 is a nuclear matrix protein involved in multiple nuclear processes. In HIV-1 infection, Matrin 3 serves as a Rev cofactor important for the cytoplasmic accumulation of HIV-1 transcripts. ZAP is a potent host restriction factor of multiple viruses including retroviruses HIV-1 and...

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Detalles Bibliográficos
Autores principales: Erazo, Angela, Goff, Stephen P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487854/
https://www.ncbi.nlm.nih.gov/pubmed/26129669
http://dx.doi.org/10.1186/s12977-015-0182-4

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