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SIRT3 Enhances Glycolysis and Proliferation in SIRT3-Expressing Gastric Cancer Cells

SIRT3 is a key NAD(+)-dependent protein deacetylase in the mitochondria of mammalian cells, functioning to prevent cell aging and transformation via regulation of mitochondrial metabolic homeostasis. However, SIRT3 is also found to express in some human tumors; its role in these SIRT3-expressing tum...

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Detalles Bibliográficos
Autores principales: Cui, Yang, Qin, Lili, Wu, Jing, Qu, Xuan, Hou, Chen, Sun, Wenyan, Li, Shiyong, Vaughan, Andrew T. M., Li, Jian Jian, Liu, Jiankang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487898/
https://www.ncbi.nlm.nih.gov/pubmed/26121691
http://dx.doi.org/10.1371/journal.pone.0129834