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SIRT3 Enhances Glycolysis and Proliferation in SIRT3-Expressing Gastric Cancer Cells
SIRT3 is a key NAD(+)-dependent protein deacetylase in the mitochondria of mammalian cells, functioning to prevent cell aging and transformation via regulation of mitochondrial metabolic homeostasis. However, SIRT3 is also found to express in some human tumors; its role in these SIRT3-expressing tum...
Autores principales: | Cui, Yang, Qin, Lili, Wu, Jing, Qu, Xuan, Hou, Chen, Sun, Wenyan, Li, Shiyong, Vaughan, Andrew T. M., Li, Jian Jian, Liu, Jiankang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487898/ https://www.ncbi.nlm.nih.gov/pubmed/26121691 http://dx.doi.org/10.1371/journal.pone.0129834 |
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