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Upregulated TCRζ improves cytokine secretion in T cells from patients with AML

Previous studies indicated that upregulating TCRζ partially recovers T cell function in patients with leukemia. In this study, we characterized the cytokine profile of TCRζ-transfected T cells from acute myeloid leukemia (AML) patients by Quantibody®Array Glass Chip. Firstly, the significantly lower...

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Detalles Bibliográficos
Autores principales: Chen, Shaohua, Zha, Xianfeng, Shi, Li, Zhou, Lingling, Yang, Lijian, Li, Bo, Wu, Xiuli, Zhong, Jun, Zhang, Tao, Lu, Yuhong, Zhu, Kanger, Li, Yangqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488036/
https://www.ncbi.nlm.nih.gov/pubmed/26081440
http://dx.doi.org/10.1186/s13045-015-0170-0