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TNF-dependent regulation and activation of innate immune cells are essential for host protection against cerebral tuberculosis
BACKGROUND: Tuberculosis (TB) affects one third of the global population, and TB of the central nervous system (CNS-TB) is the most severe form of tuberculosis which often associates with high mortality. The pro-inflammatory cytokine tumour necrosis factor (TNF) plays a critical role in the initial...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488051/ https://www.ncbi.nlm.nih.gov/pubmed/26112704 http://dx.doi.org/10.1186/s12974-015-0345-1 |