TNF-dependent regulation and activation of innate immune cells are essential for host protection against cerebral tuberculosis

BACKGROUND: Tuberculosis (TB) affects one third of the global population, and TB of the central nervous system (CNS-TB) is the most severe form of tuberculosis which often associates with high mortality. The pro-inflammatory cytokine tumour necrosis factor (TNF) plays a critical role in the initial...

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Detalles Bibliográficos
Autores principales: Francisco, Ngiambudulu M., Hsu, Nai-Jen, Keeton, Roanne, Randall, Philippa, Sebesho, Boipelo, Allie, Nasiema, Govender, Dhirendra, Quesniaux, Valerie, Ryffel, Bernhard, Kellaway, Lauriston, Jacobs, Muazzam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488051/
https://www.ncbi.nlm.nih.gov/pubmed/26112704
http://dx.doi.org/10.1186/s12974-015-0345-1

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