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Triphala Extract Suppresses Proliferation and Induces Apoptosis in Human Colon Cancer Stem Cells via Suppressing c-Myc/Cyclin D1 and Elevation of Bax/Bcl-2 Ratio

Colon cancer is the second leading cause of cancer related deaths in the USA. Cancer stem cells (CSCs) have the ability to drive continued expansion of the population of malignant cells. Therefore, strategies that target CSCs could be effective against colon cancer and in reducing the risk of relaps...

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Detalles Bibliográficos
Autores principales: Vadde, Ramakrishna, Radhakrishnan, Sridhar, Reddivari, Lavanya, Vanamala, Jairam K. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488090/
https://www.ncbi.nlm.nih.gov/pubmed/26167492
http://dx.doi.org/10.1155/2015/649263