Cargando…

Triphala Extract Suppresses Proliferation and Induces Apoptosis in Human Colon Cancer Stem Cells via Suppressing c-Myc/Cyclin D1 and Elevation of Bax/Bcl-2 Ratio

Colon cancer is the second leading cause of cancer related deaths in the USA. Cancer stem cells (CSCs) have the ability to drive continued expansion of the population of malignant cells. Therefore, strategies that target CSCs could be effective against colon cancer and in reducing the risk of relaps...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vadde, Ramakrishna, Radhakrishnan, Sridhar, Reddivari, Lavanya, Vanamala, Jairam K. P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488090/ https://www.ncbi.nlm.nih.gov/pubmed/26167492 http://dx.doi.org/10.1155/2015/649263

Ejemplares similares

Resveratrol suppresses IGF-1 induced human colon cancer cell proliferation and elevates apoptosis via suppression of IGF-1R/Wnt and activation of p53 signaling pathways
por: Vanamala, Jairam, et al.
Publicado: (2010)

Grape compounds suppress colon cancer stem cells in vitro and in a rodent model of colon carcinogenesis
por: Reddivari, Lavanya, et al.
Publicado: (2016)

Eugenia jambolana (Java Plum) Fruit Extract Exhibits Anti-Cancer Activity against Early Stage Human HCT-116 Colon Cancer Cells and Colon Cancer Stem Cells
por: Charepalli, Venkata, et al.
Publicado: (2016)

Resveratrol suppresses human colon cancer cell proliferation and induces apoptosis via targeting the pentose phosphate and the talin-FAK signaling pathways-A proteomic approach
por: Vanamala, Jairam, et al.
Publicado: (2011)

Characterization of Microbial Dysbiosis and Metabolomic Changes in Dogs with Acute Diarrhea
por: Guard, Blake C., et al.
Publicado: (2015)

miR-145 suppresses the proliferation, invasion and migration of NSCLC cells by regulating the BAX/BCL-2 ratio and the caspase-3 cascade
por: Pan, Yi, et al.
Publicado: (2018)

The effect of moderate exercise on the elevation of Bax/Bcl-2 ratio in oral squamous epithelial cells induced by benzopyrene
por: Irmawati, Anis, et al.
Publicado: (2018)

MicroRNA-497 Induces Apoptosis and Suppresses Proliferation via the Bcl-2/Bax-Caspase9-Caspase3 Pathway and Cyclin D2 Protein in HUVECs
por: Wu, Ridong, et al.
Publicado: (2016)

Association of Bax Expression and Bcl2/Bax Ratio with Clinical and Molecular Prognostic Markers in Chronic Lymphocytic Leukemia
por: Vucicevic, Ksenija, et al.
Publicado: (2016)

Analysis of the Polymorphisms and Expression Levels of the BCL2, BAX and c-MYC Genes in Patients with Ovarian Cancer
por: Olbromski, Piotr Józef, et al.
Publicado: (2023)

Bax/Bcl-2 expression ratio in prediction of response to breast cancer radiotherapy
por: Azimian, Hosein, et al.
Publicado: (2018)

Expression of c-Myc, Bcl2, Bcl6, and Cyclin D1 in High-Grade B-Cell Lymphoma
por: Ali, Seemal, et al.
Publicado: (2022)

Bax, Bcl-2, and Bax/Bcl-2 as prognostic markers in acute myeloid leukemia: are we ready for Bcl-2-directed therapy?
por: Kulsoom, Bibi, et al.
Publicado: (2018)

Anticataract potential of Triphala
por: Wiwanitkit, Viroj
Publicado: (2011)

Role of Triphala in dentistry
por: Prakash, Shobha, et al.
Publicado: (2014)

Exendin-4 protects retinal cells from early diabetes in Goto-Kakizaki rats by increasing the Bcl-2/Bax and Bcl-xL/Bax ratios and reducing reactive gliosis
por: Fan, Yichao, et al.
Publicado: (2014)

Triphala Suppresses Growth and Migration of Human Gastric Carcinoma Cells In Vitro and in a Zebrafish Xenograft Model
por: Tsering, Jokyab, et al.
Publicado: (2018)

Sepia Ink Oligopeptide Induces Apoptosis in Prostate Cancer Cell Lines via Caspase-3 Activation and Elevation of Bax/Bcl-2 Ratio
por: Huang, Fangfang, et al.
Publicado: (2012)

Zerumbone induced apoptosis in liver cancer cells via modulation of Bax/Bcl-2 ratio
por: Sharifah Sakinah, SA, et al.
Publicado: (2007)

Bcl-2/Bax ratios in chronic lymphocytic leukaemia and their correlation with in vitro apoptosis and clinical resistance.
por: Williamson, K. E., et al.
Publicado: (1998)

Bcl-2/Bax ratios in chronic lymphocytic leukaemia and their correlation with in vitro apoptosis and clinical resistance.
por: Pepper, C., et al.
Publicado: (1997)

The Action of Bax and Bcl-2 on T Cell Selection
por: Williams, Owen, et al.
Publicado: (1998)

PB1821: THE INFLUENCE OF BCL2, BAX, BAX/BCL2 RATIO AND MDR1 GENE EXPRESSION ON PROGNOSIS OF ADULT DE NOVO ACUTE MYELOID LEUKEMIA PATIENTS WITH NORMAL KARYOTYPE
por: Pravdic, Zlatko, et al.
Publicado: (2023)

Hyperglycemia Promotes Chemoresistance Through the Reduction of the Mitochondrial DNA Damage, the Bax/Bcl-2 and Bax/Bcl-XL Ratio, and the Cells in Sub-G1 Phase Due to Antitumoral Drugs Induced-Cytotoxicity in Human Colon Adenocarcinoma Cells
por: Bergandi, Loredana, et al.
Publicado: (2018)

PHARMACOGNOSTICAL INVESTIGATIONS ON TRIPHALA CHURNAM
por: Ashokkumar, D.
Publicado: (2007)

More concerns on triphala mouthwash
por: Wiwanitkit, Viroj
Publicado: (2010)

Bcl-2/Bax protein ratio predicts 5-fluorouracil sensitivity independently of p53 status
por: Mirjolet, J-F, et al.
Publicado: (2000)

Bcl-2/Bax ratios in chronic lymphocytic leukaemia and their correlation with in vitro apoptosis and clinical responsiveness - reply
por: Bentley, P, et al.
Publicado: (1998)

Is Bax/Bcl-2 Ratio Considered as a Prognostic Marker with Age and Tumor Location in Colorectal Cancer?
por: Khodapasand, Ehsan, et al.
Publicado: (2015)

Bcl-XL Inhibits Membrane Permeabilization by Competing with Bax
por: Billen, Lieven P, et al.
Publicado: (2008)

Nucleophosmin Mutations Induce Chemosensitivity in THP-1 Leukemia Cells by Suppressing NF-κB Activity and Regulating Bax/Bcl-2 Expression
por: Zhang, Shuaishuai, et al.
Publicado: (2016)

Triacontanoic ester of 5ʹʹ-hydroxyjustisolin: Tumour suppressive role in cervical cancer via Bcl-2, BAX and caspase-3 mediated signalling
por: Joseph, Litty, et al.
Publicado: (2019)

Enhanced levels of the apoptotic BAX/BCL-2 ratio in children with acute lymphoblastic leukemia and high-risk features
por: Kaparou, Maria, et al.
Publicado: (2013)

Heartwood extract of Acacia catechu induces apoptosis in human breast carcinoma by altering bax/bcl-2 ratio
por: Ghate, Nikhil Baban, et al.
Publicado: (2014)

ROLE OF TRIPHALA IN THE MANAGEMENT OF PERIDONTAL DISEASE
por: Maurya, D.K, et al.
Publicado: (1997)

Effect of Triphala mouthwash on the caries status
por: Tandon, Shobha, et al.
Publicado: (2010)

Therapeutic Uses of Triphala in Ayurvedic Medicine
por: Peterson, Christine Tara, et al.
Publicado: (2017)

Cordycepin inhibits colon cancer proliferation by suppressing MYC expression
por: Zhang, Zhe, et al.
Publicado: (2022)

Perinatal Bisphenol A Exposure Induces Chronic Inflammation in Rabbit Offspring via Modulation of Gut Bacteria and Their Metabolites
por: Reddivari, Lavanya, et al.
Publicado: (2017)

Expression of Apoptotic Markers Bcl-2 and Bax in the Vascular Wall
por: Klimentova, E.A., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_9lpbqr6p0t0uf50ftmbekap15o