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Uncovering correlated variability in epigenomic datasets using the Karhunen-Loeve transform
BACKGROUND: Larger variation exists in epigenomes than in genomes, as a single genome shapes the identity of multiple cell types. With the advent of next-generation sequencing, one of the key problems in computational epigenomics is the poor understanding of correlations and quantitative differences...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488123/ https://www.ncbi.nlm.nih.gov/pubmed/26140054 http://dx.doi.org/10.1186/s13040-015-0051-7 |