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A Triterpenoid Inhibited Hormone-Induced Adipocyte Differentiation and Alleviated Dexamethasone-Induced Insulin Resistance in 3T3-L1 adipocytes

ABSTRACT: 6α-Hydroxylup-20(29)-en-3-on-28-oic acid (1), a natural triterpenoid, was found to possess the ability in a dose-dependent manner inhibiting hormone-induced adipocyte differentiation in 3T3-L1 preadipocytes, and restoring glucose consuming ability in dexamethasone (DXM)-induced insulin res...

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Detalles Bibliográficos
Autores principales: Qin, Ji-Huan, Ma, Jun-Zeng, Yang, Xing-Wei, Hu, Ying-Jie, Zhou, Juan, Fu, Lin-Chun, Tian, Ru-Hua, Liu, Shan, Xu, Gang, Shen, Xiao-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488152/
https://www.ncbi.nlm.nih.gov/pubmed/26077651
http://dx.doi.org/10.1007/s13659-015-0063-5