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Biocomparison of Three Formulations of the S1P(1) Receptor Modulator Ponesimod in Healthy Subjects

BACKGROUND: Ponesimod is a potent selective sphingosine-1-phosphate receptor 1 (S1P(1)) modulator, which leads to a reduction in circulating lymphocytes, reflecting their sequestration within lymphoid organs. Modulation of the S1P(1) receptor has been previously described to be an effective treatmen...

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Detalles Bibliográficos
Autores principales: Juif, Pierre-Eric, Hoch, Matthias, D’Ambrosio, Daniele, Dingemanse, Jasper
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488184/
https://www.ncbi.nlm.nih.gov/pubmed/25939333
http://dx.doi.org/10.1007/s40268-015-0095-7