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Biocomparison of Three Formulations of the S1P(1) Receptor Modulator Ponesimod in Healthy Subjects
BACKGROUND: Ponesimod is a potent selective sphingosine-1-phosphate receptor 1 (S1P(1)) modulator, which leads to a reduction in circulating lymphocytes, reflecting their sequestration within lymphoid organs. Modulation of the S1P(1) receptor has been previously described to be an effective treatmen...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488184/ https://www.ncbi.nlm.nih.gov/pubmed/25939333 http://dx.doi.org/10.1007/s40268-015-0095-7 |