Lisdexamfetamine Dimesylate Effects on the Pharmacokinetics of Cytochrome P450 Substrates in Healthy Adults in an Open-Label, Randomized, Crossover Study

INTRODUCTION: This open-label, randomized, two-period drug interaction study assessed lisdexamfetamine dimesylate (LDX) effects on cytochrome P450 (CYP) enzyme (CYP1A2, CYP2D6, CYP2C19, and CYP3A) activity. METHODS: Thirty healthy volunteers were administered the Cooperstown cocktail (CYP1A2 [caffei...

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Detalles Bibliográficos
Autores principales: Ermer, James, Corcoran, Mary, Martin, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488187/
https://www.ncbi.nlm.nih.gov/pubmed/25862215
http://dx.doi.org/10.1007/s40268-015-0090-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488187/
https://www.ncbi.nlm.nih.gov/pubmed/25862215
http://dx.doi.org/10.1007/s40268-015-0090-z

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