Cargando…

Resibufogenin Induces G1-Phase Arrest through the Proteasomal Degradation of Cyclin D1 in Human Malignant Tumor Cells

Huachansu, a traditional Chinese medicine prepared from the dried toad skin, has been used in clinical studies for various cancers in China. Resibufogenin is a component of huachansu and classified as bufadienolides. Resibufogenin has been shown to exhibit the anti-proliferative effect against cance...

Descripción completa

Detalles Bibliográficos
Autores principales: Ichikawa, Masami, Sowa, Yoshihiro, Iizumi, Yosuke, Aono, Yuichi, Sakai, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488249/
https://www.ncbi.nlm.nih.gov/pubmed/26121043
http://dx.doi.org/10.1371/journal.pone.0129851