A Potential Role for the Inhibition of PI3K Signaling in Glioblastoma Therapy

Glioblastoma multiforme (GBM) is the most common primary brain tumor and among the most difficult to treat malignancies per se. In almost 90% of all GBM alterations in the PI3K/Akt/mTOR have been found, making this survival cascade a promising therapeutic target, particular for combination therapy t...

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Detalles Bibliográficos
Autores principales: Ströbele, Stephanie, Schneider, Matthias, Schneele, Lukas, Siegelin, Markus D., Nonnenmacher, Lisa, Zhou, Shaoxia, Karpel-Massle, Georg, Westhoff, Mike-Andrew, Halatsch, Marc-Eric, Debatin, Klaus-Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488267/
https://www.ncbi.nlm.nih.gov/pubmed/26121251
http://dx.doi.org/10.1371/journal.pone.0131670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488267/
https://www.ncbi.nlm.nih.gov/pubmed/26121251
http://dx.doi.org/10.1371/journal.pone.0131670

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