Cargando…

NLRP7, Involved in Hydatidiform Molar Pregnancy (HYDM1), Interacts with the Transcriptional Repressor ZBTB16

Mutations in the maternal effect gene NLRP7 cause biparental hydatidiform mole (HYDM1). HYDM1 is characterized by abnormal growth of placenta and lack of proper embryonic development. The molar tissues are characterized by abnormal methylation patterns at differentially methylated regions (DMRs) of...

Descripción completa

Detalles Bibliográficos
Autores principales: Singer, Heike, Biswas, Arijit, Nuesgen, Nicole, Oldenburg, Johannes, El-Maarri, Osman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488268/
https://www.ncbi.nlm.nih.gov/pubmed/26121690
http://dx.doi.org/10.1371/journal.pone.0130416