Inhibition of the Prostaglandin Transporter PGT Lowers Blood Pressure in Hypertensive Rats and Mice

Inhibiting the synthesis of endogenous prostaglandins with nonsteroidal anti-inflammatory drugs exacerbates arterial hypertension. We hypothesized that the converse, i.e., raising the level of endogenous prostaglandins, might have anti-hypertensive effects. To accomplish this, we focused on inhibiti...

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Detalles Bibliográficos
Autores principales: Chi, Yuling, Jasmin, Jean-Francois, Seki, Yoshinori, Lisanti, Michael P., Charron, Maureen J., Lefer, David J., Schuster, Victor L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488299/
https://www.ncbi.nlm.nih.gov/pubmed/26121580
http://dx.doi.org/10.1371/journal.pone.0131735

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488299/
https://www.ncbi.nlm.nih.gov/pubmed/26121580
http://dx.doi.org/10.1371/journal.pone.0131735

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