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Inhibition of the Prostaglandin Transporter PGT Lowers Blood Pressure in Hypertensive Rats and Mice
Inhibiting the synthesis of endogenous prostaglandins with nonsteroidal anti-inflammatory drugs exacerbates arterial hypertension. We hypothesized that the converse, i.e., raising the level of endogenous prostaglandins, might have anti-hypertensive effects. To accomplish this, we focused on inhibiti...
Autores principales: | Chi, Yuling, Jasmin, Jean-Francois, Seki, Yoshinori, Lisanti, Michael P., Charron, Maureen J., Lefer, David J., Schuster, Victor L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488299/ https://www.ncbi.nlm.nih.gov/pubmed/26121580 http://dx.doi.org/10.1371/journal.pone.0131735 |
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