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Identification of Essential Proteins Based on a New Combination of Local Interaction Density and Protein Complexes

BACKGROUND: Computational approaches aided by computer science have been used to predict essential proteins and are faster than expensive, time-consuming, laborious experimental approaches. However, the performance of such approaches is still poor, making practical applications of computational appr...

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Detalles Bibliográficos
Autores principales: Luo, Jiawei, Qi, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488326/
https://www.ncbi.nlm.nih.gov/pubmed/26125187
http://dx.doi.org/10.1371/journal.pone.0131418