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Genetic Analysis of T Cell Lymphomas in Carbon Ion-Irradiated Mice Reveals Frequent Interstitial Chromosome Deletions: Implications for Second Cancer Induction in Normal Tissues during Carbon Ion Radiotherapy

Monitoring mice exposed to carbon ion radiotherapy provides an indirect method to evaluate the potential for second cancer induction in normal tissues outside the radiotherapy target volume, since such estimates are not yet possible from historical patient data. Here, male and female B6C3F1 mice wer...

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Detalles Bibliográficos
Autores principales: Blyth, Benjamin J., Kakinuma, Shizuko, Sunaoshi, Masaaki, Amasaki, Yoshiko, Hirano-Sakairi, Shinobu, Ogawa, Kanae, Shirakami, Ayana, Shang, Yi, Tsuruoka, Chizuru, Nishimura, Mayumi, Shimada, Yoshiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488329/
https://www.ncbi.nlm.nih.gov/pubmed/26125582
http://dx.doi.org/10.1371/journal.pone.0130666