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A Comparative Study of Early Afterdepolarization-Mediated Fibrillation in Two Mathematical Models for Human Ventricular Cells

Early afterdepolarizations (EADs), which are abnormal oscillations of the membrane potential at the plateau phase of an action potential, are implicated in the development of cardiac arrhythmias like Torsade de Pointes. We carry out extensive numerical simulations of the TP06 and ORd mathematical mo...

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Detalles Bibliográficos
Autores principales: Zimik, Soling, Vandersickel, Nele, Nayak, Alok Ranjan, Panfilov, Alexander V., Pandit, Rahul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488347/
https://www.ncbi.nlm.nih.gov/pubmed/26125185
http://dx.doi.org/10.1371/journal.pone.0130632