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Isolation and characterization of arylacetamide deacetylase in cynomolgus macaques

Arylacetamide deacetylase (AADAC), a microsomal serine esterase, hydrolyzes drugs, such as flutamide, phenacetin and rifampicin. Because AADAC has not been fully investigated at molecular levels in cynomolgus macaques, the non-human primate species widely used in drug metabolism studies, cynomolgus...

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Detalles Bibliográficos
Autores principales: UNO, Yasuhiro, HOSOKAWA, Masakiyo, IMAI, Teruko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488411/
https://www.ncbi.nlm.nih.gov/pubmed/25715734
http://dx.doi.org/10.1292/jvms.14-0496