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Isolation and characterization of arylacetamide deacetylase in cynomolgus macaques
Arylacetamide deacetylase (AADAC), a microsomal serine esterase, hydrolyzes drugs, such as flutamide, phenacetin and rifampicin. Because AADAC has not been fully investigated at molecular levels in cynomolgus macaques, the non-human primate species widely used in drug metabolism studies, cynomolgus...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Japanese Society of Veterinary Science
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488411/ https://www.ncbi.nlm.nih.gov/pubmed/25715734 http://dx.doi.org/10.1292/jvms.14-0496 |