A Novel Once-Daily Fixed-Dose Combination of Memantine Extended Release and Donepezil for the Treatment of Moderate to Severe Alzheimer’s Disease: Two Phase I Studies in Healthy Volunteers

BACKGROUND: Combining two standard-of-care medications for Alzheimer’s disease (AD) into a single once-daily dosage unit may improve treatment adherence, facilitate drug administration, and reduce caregiver burden. A new fixed-dose combination (FDC) capsule containing 28 mg memantine extended releas...

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Detalles Bibliográficos
Autores principales: Boinpally, Ramesh, Chen, Laishun, Zukin, Stephen R., McClure, Natalie, Hofbauer, Robert K., Periclou, Antonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488451/
https://www.ncbi.nlm.nih.gov/pubmed/26016820
http://dx.doi.org/10.1007/s40261-015-0296-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488451/
https://www.ncbi.nlm.nih.gov/pubmed/26016820
http://dx.doi.org/10.1007/s40261-015-0296-4

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