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Next-Generation Covalent Irreversible Kinase Inhibitors in NSCLC: Focus on Afatinib
First-generation, reversible epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs), erlotinib and gefitinib, represented an important addition to the treatment armamentarium for non-small-cell lung cancer (NSCLC) patients with activating EGFR mutations. However, all patients inev...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer International Publishing
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488453/ https://www.ncbi.nlm.nih.gov/pubmed/26123538 http://dx.doi.org/10.1007/s40259-015-0130-9 |