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A Genetic Porcine Model of Cancer

The large size of the pig and its similarity in anatomy, physiology, metabolism, and genetics to humans make it an ideal platform to develop a genetically defined, large animal model of cancer. To this end, we created a transgenic “oncopig” line encoding Cre recombinase inducible porcine transgenes...

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Detalles Bibliográficos
Autores principales: Schook, Lawrence B., Collares, Tiago V., Hu, Wenping, Liang, Ying, Rodrigues, Fernanda M., Rund, Laurie A., Schachtschneider, Kyle M., Seixas, Fabiana K., Singh, Kuldeep, Wells, Kevin D., Walters, Eric M., Prather, Randall S., Counter, Christopher M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488487/
https://www.ncbi.nlm.nih.gov/pubmed/26132737
http://dx.doi.org/10.1371/journal.pone.0128864