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A Genetic Porcine Model of Cancer
The large size of the pig and its similarity in anatomy, physiology, metabolism, and genetics to humans make it an ideal platform to develop a genetically defined, large animal model of cancer. To this end, we created a transgenic “oncopig” line encoding Cre recombinase inducible porcine transgenes...
Autores principales: | Schook, Lawrence B., Collares, Tiago V., Hu, Wenping, Liang, Ying, Rodrigues, Fernanda M., Rund, Laurie A., Schachtschneider, Kyle M., Seixas, Fabiana K., Singh, Kuldeep, Wells, Kevin D., Walters, Eric M., Prather, Randall S., Counter, Christopher M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488487/ https://www.ncbi.nlm.nih.gov/pubmed/26132737 http://dx.doi.org/10.1371/journal.pone.0128864 |
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