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Combined effect of bisphosphonate and recombinant human bone morphogenetic protein 2 on bone healing of rat calvarial defects

BACKGROUND: This study aimed to investigate new bone formation using recombinant human bone morphogenetic protein 2 (rhBMP-2) and locally applied bisphosphonate in rat calvarial defects. METHODS: Thirty-six rats were studied. Two circular 5 mm diameter bony defect were formed in the calvaria using a...

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Detalles Bibliográficos
Autores principales: Kim, Ho-Chul, Song, Jae-Min, Kim, Chang-Joo, Yoon, Sang-Yong, Kim, In-Ryoung, Park, Bong-Soo, Shin, Sang-Hun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488498/
https://www.ncbi.nlm.nih.gov/pubmed/26161381
http://dx.doi.org/10.1186/s40902-015-0015-3