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Genetic Mosaics and the Germ Line Lineage

Genetic mosaics provide information about cellular lineages that is otherwise difficult to obtain, especially in humans. De novo mutations act as cell markers, allowing the tracing of developmental trajectories of all descendants of the cell in which the new mutation arises. De novo mutations may ar...

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Detalles Bibliográficos
Autores principales: Samuels, Mark E., Friedman, Jan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488662/
https://www.ncbi.nlm.nih.gov/pubmed/25898403
http://dx.doi.org/10.3390/genes6020216