Proteasome as a Molecular Target of Microcystin-LR

Proteasome degrades proteins in eukaryotic cells. As such, the proteasome is crucial in cell cycle and function. This study proved that microcystin-LR (MC-LR), which is a toxic by-product of algal bloom, can target cellular proteasome and selectively inhibit proteasome trypsin-like (TL) activity. MC...

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Detalles Bibliográficos
Autores principales: Zhu, Zhu, Zhang, Li, Shi, Guoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488699/
https://www.ncbi.nlm.nih.gov/pubmed/26090622
http://dx.doi.org/10.3390/toxins7062221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488699/
https://www.ncbi.nlm.nih.gov/pubmed/26090622
http://dx.doi.org/10.3390/toxins7062221

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