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Evaluation of Signature Erosion in Ebola Virus Due to Genomic Drift and Its Impact on the Performance of Diagnostic Assays

Genome sequence analyses of the 2014 Ebola Virus (EBOV) isolates revealed a potential problem with the diagnostic assays currently in use; i.e., drifting genomic profiles of the virus may affect the sensitivity or even produce false-negative results. We evaluated signature erosion in ebolavirus mole...

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Detalles Bibliográficos
Autores principales: Sozhamannan, Shanmuga, Holland, Mitchell Y., Hall, Adrienne T., Negrón, Daniel A., Ivancich, Mychal, Koehler, Jeffrey W., Minogue, Timothy D., Campbell, Catherine E., Berger, Walter J., Christopher, George W., Goodwin, Bruce G., Smith, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488730/
https://www.ncbi.nlm.nih.gov/pubmed/26090727
http://dx.doi.org/10.3390/v7062763