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Evaluation of Signature Erosion in Ebola Virus Due to Genomic Drift and Its Impact on the Performance of Diagnostic Assays
Genome sequence analyses of the 2014 Ebola Virus (EBOV) isolates revealed a potential problem with the diagnostic assays currently in use; i.e., drifting genomic profiles of the virus may affect the sensitivity or even produce false-negative results. We evaluated signature erosion in ebolavirus mole...
Autores principales: | Sozhamannan, Shanmuga, Holland, Mitchell Y., Hall, Adrienne T., Negrón, Daniel A., Ivancich, Mychal, Koehler, Jeffrey W., Minogue, Timothy D., Campbell, Catherine E., Berger, Walter J., Christopher, George W., Goodwin, Bruce G., Smith, Michael A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488730/ https://www.ncbi.nlm.nih.gov/pubmed/26090727 http://dx.doi.org/10.3390/v7062763 |
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