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miR-23a impairs bone differentiation in osteosarcoma via down-regulation of GJA1

Osteosarcoma is the most common type of bone cancer in children and adolescents. Impaired differentiation of osteoblast cells is a distinguishing feature of this aggressive disease. As improvements in survival outcomes have largely plateaued, better understanding of the bone differentiation program...

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Detalles Bibliográficos
Autores principales: Gindin, Yevgeniy, Jiang, Yuan, Francis, Princy, Walker, Robert L., Abaan, Ogan D., Zhu, Yuelin J., Meltzer, Paul S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488756/
https://www.ncbi.nlm.nih.gov/pubmed/26191074
http://dx.doi.org/10.3389/fgene.2015.00233