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miR-23a impairs bone differentiation in osteosarcoma via down-regulation of GJA1
Osteosarcoma is the most common type of bone cancer in children and adolescents. Impaired differentiation of osteoblast cells is a distinguishing feature of this aggressive disease. As improvements in survival outcomes have largely plateaued, better understanding of the bone differentiation program...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488756/ https://www.ncbi.nlm.nih.gov/pubmed/26191074 http://dx.doi.org/10.3389/fgene.2015.00233 |