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Bardoxolone Methyl Prevents Fat Deposition and Inflammation in Brown Adipose Tissue and Enhances Sympathetic Activity in Mice Fed a High-Fat Diet

Obesity results in changes in brown adipose tissue (BAT) morphology, leading to fat deposition, inflammation, and alterations in sympathetic nerve activity. Bardoxolone methyl (BARD) has been extensively studied for the treatment of chronic diseases. We present for the first time the effects of oral...

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Detalles Bibliográficos
Autores principales: Dinh, Chi H. L., Szabo, Alexander, Yu, Yinghua, Camer, Danielle, Zhang, Qingsheng, Wang, Hongqin, Huang, Xu-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488809/
https://www.ncbi.nlm.nih.gov/pubmed/26066016
http://dx.doi.org/10.3390/nu7064705