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Bardoxolone Methyl Prevents Fat Deposition and Inflammation in Brown Adipose Tissue and Enhances Sympathetic Activity in Mice Fed a High-Fat Diet
Obesity results in changes in brown adipose tissue (BAT) morphology, leading to fat deposition, inflammation, and alterations in sympathetic nerve activity. Bardoxolone methyl (BARD) has been extensively studied for the treatment of chronic diseases. We present for the first time the effects of oral...
Autores principales: | Dinh, Chi H. L., Szabo, Alexander, Yu, Yinghua, Camer, Danielle, Zhang, Qingsheng, Wang, Hongqin, Huang, Xu-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488809/ https://www.ncbi.nlm.nih.gov/pubmed/26066016 http://dx.doi.org/10.3390/nu7064705 |
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